The Choline Content of Rats on Various Choline-free Diets*
نویسندگان
چکیده
Choline synthesis in the rat is intimated by the fact that methionine can replace choline in preventing fatty livers (l), and by the observation that labeled methyl groups can be transferred from methionine to choline (2). However, the development of fatty livers (3) and of hemorrhagic kidneys (4) and the restricted growth (5, 6) in rats on low choline diets all suggest that preformed choline must be supplied in the diet for optimal physiological performance in this species. Choline appears to be an indispensable constituent of the diet for the chicken (7, 8). It is therefore desirable to have information on the choline content of the tissues of rats maintained on diets low in choline. This was obtained by means of a direct analytical technique.
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